The Sloan-Kettering Institute, Memorial Sloan-Kettering's basic science research arm, located on the main campus, conducts innovative programs in Cancer Biology and Genetics, Cell Biology, Computational Biology, Developmental Biology, Immunology, Molecular Biology, Molecular Pharmacology and Chemistry, and Structural Biology. Major scientific efforts are under way in the areas of:

• Signals and pathways involved in the control of cell proliferation
• Regulatory pathways involved in developmental biology and the control of cell differentiation
• Cell-cell interactions, adhesion, and protein targeting
• Tumor immunology, immunotherapy, and transplantation biology
• Human cancer genetics and molecular pathology
• Drug development, drug resistance, and clinical therapeutics